The brothers, who say they are innocent, are accused of having formed an organised criminal network in early 2021 in Romania, as well as in the US and Britain
A team at the University College London found the small molecule drug caused the disappearance of a protein called SAP, thought to be involved in the disease, from the brains of five Alzheimer’s patients who took it for three months.
The results were published in the journal Proceedings of the National Academy of Science.
Britain’s Alzheimer’s Research Trust, which helped fund the research, said the results with the drug, CPHPC, were cause for “cautious optimism”, but it was too soon to know for sure if removing SAP from the brain would provide clinical benefit.
Larger scale clinical studies are now planned.
“New treatments for Alzheimer’s disease are desperately needed, and it’s possible that this small molecule could be a future candidate,” said Trust Chief Executive Rebecca Wood.
Given the world’s ageing population and the lack of an effective treatment, new medicines for Alzheimer’s are seen as a major untapped opportunity for the pharmaceutical industry.
The field, however, is littered with past failures.
Among the furthest advanced experimental drugs for Azheimer’s is bapineuzumab from Elan and Wyeth—now being acquired by Pfizer—which produced disappointing clinical trial results last summer.
The brothers, who say they are innocent, are accused of having formed an organised criminal network in early 2021 in Romania, as well as in the US and Britain
The left-handed batter scored 3369 runs in 136 one-day internationals and 2893 in 140 Twenty20 internationals — both Pakistan records
Food supplies were distributed to 80 households
On January 31, a heart was airlifted from Delhi to Chennai, paving the way for Ayesha Rashid's life-saving surgery
The online retailer, which is headquartered in Singapore, has said it has around 108 million monthly active users in the 27-nation EU
The baby girl named Rouh, meaning Soul, suffered respiratory problems and a weak immune system, a doctor at the Emirati Hospital in Rafah said
Specialised teams are currently managing the situation by cleaning up and removing the dead fish
The charges against them include planning terrorist acts, fundraising for the Organisation, and concealing the source and destination of those funds