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Pfizer and BioNTech announced on Thursday they would seek regulatory authorisation for a third dose of their Covid-19 vaccine.
It comes after initial data from an ongoing trial showed a third shot pushed antibody levels five to 10 times higher against the original coronavirus strain and the Beta variant, first found in South Africa, compared to the first two doses alone, according to a statement.
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"The companies expect to publish more definitive data soon as well as in a peer-reviewed journal and plan to submit the data to the FDA (Food and Drug Administration), EMA (European Medicines Agency) and other regulatory authorities in the coming weeks," the statement said.
In addition, the companies expect that a third dose will perform similarly well against the highly transmissible Delta strain, which is quickly becoming globally dominant.
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Out of caution, the companies are also developing a Delta-specific vaccine, the first batch of which has been manufactured at BioNTech's facility in Mainz, Germany.
The companies anticipate the clinical studies will begin in August, subject to regulatory approvals.
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The companies added that they believe that a third dose may be needed within six to 12 months after full vaccinaCovid-19: UAE becomes world’s most vaccinated nation
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"While protection against severe disease remained high across the full 6 months, a decline in efficacy against symptomatic disease over time and the continued emergence of variants are expected," the statement said.
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