Other early winners on Tuesday included Taylor Townsend and Astra Sharma
In a match that finished four and a half hours after it started due to two rain delays, clay court king Nadal was never troubled.
His victory matched the mark of 17 Masters wins set by Andre Agassi, although the American was 34 when he won the last of his while the Spaniard is still just 23.
Nadal clearly coped better than Ferrer, who was aiming for a first ever Masters title, with the rain as until the first break it was 4-4 and 40-15 to Ferrer on his own serve.
However, he won only three more games after the heavens opened and Nadal, who has dropped only one set on clay this year, proved that he is in great shape ahead of the French Open, the second Grand Slam of the year.
Two weeks ago he stormed to victory at the Monte Carlo Masters and here he was only troubled in his three-set epic against Latvia’s Ernests Gulbis in the semi-finals.
Other early winners on Tuesday included Taylor Townsend and Astra Sharma
Sinner has been on a roll this season, winning the Australian Open for what is expected to be the first of many Grand Slam titles
The Australian Open champion will move to a career-high second in the ATP world rankings after winning the third title of the season
Zverev's win marked his return to the Miami Open semifinals for the first time since his runner-up finish in 2018
The victory marked the first time Collins has won five consecutive matches on the WTA Tour since the 2022 Australian Open
The Serb had brought Croatia's 2001 Wimbledon champion on board as a member of the coaching team ahead of the grass court Grand Slam in 2019
Playing in her home tournament in southern Florida, Gauff fell 6-3 1-6 6-2 to Frenchwoman Garcia in the fourth round on a day of upsets
The Belarusian, whose former boyfriend died on Tuesday, vented her frustration by smashing her racquet to pieces after losing the match