He also stabbed three other workers, leaving them with serious injuries
uae4 hours ago
US researchers have developed a potential new vaccine, which has proven effective against the original SARS-CoV-1, SARS-CoV-2 as well as its UK, South Africa and Brazil variants and related bat Coronaviruses that could potentially cause the next pandemic.
The new vaccine, called pan-coronavirus vaccine, was found effective in protecting monkeys and mice.
Pan-coronavirus vaccine triggers neutralising antibodies via a nanoparticle. The nanoparticle is composed of the coronavirus part that allows it to bind to the body's cell receptors and is formulated with a chemical booster called an adjuvant. Success in primates is highly relevant to humans, said researchers from the Duke University in North Carolina, US.
The findings, published in the journal Nature, showed that the nanoparticle vaccine, in monkeys, blocked Covid-19 infection by 100 per cent. The new vaccine also elicited significantly higher neutralising levels in the animals than current vaccine platforms or natural infection in humans.
"We began this work last spring with the understanding that, like all viruses, mutations would occur in the SARS-CoV-2 virus, which causes Covid-19," said senior author Barton F Haynes, director of the Duke Human Vaccine Institute (DHVI).
"The mRNA vaccines were already under development, so we were looking for ways to sustain their efficacy once those variants appeared.
"This approach not only provided protection against SARS-CoV-2, but the antibodies induced by the vaccine also neutralised variants of concern that originated in the UK, South Africa and Brazil. And the induced antibodies reacted with quite a large panel of coronaviruses," Haynes said.
The team built on earlier studies involving SARS, the respiratory illness caused by a coronavirus called SARS-CoV-1. They found a person who had been infected with SARS developed antibodies capable of neutralising multiple coronaviruses, suggesting that a pan-coronavirus might be possible.
They identified one particular receptor-binding domain site that is present on SARS-CoV-2, its circulating variants and SARS-related bat viruses that makes them highly vulnerable to cross-neutralising antibodies.
The team then designed a nanoparticle displaying this vulnerable spot. The nanoparticle is combined with a small molecule adjuvant, which boosts the body's immune response to fight the disease.
He also stabbed three other workers, leaving them with serious injuries
uae4 hours ago
Dubai FinTech Summit kicked off on Monday with over 200 exhibitors
business5 hours ago
There were no immediate details over what the agreement entailed
mena5 hours ago
Authorities are currently investigating the sightings
uae5 hours ago
Although Israel ordered civilians in Rafah to evacuate, charity organisations say no real plan for their move is in place
mena5 hours ago
On Sunday, the final day of the adult competition, the UAE national team delivered a stellar performance, adding seven more medals to their tally
sports5 hours ago
Report says MAI-1 will be "far larger" than the previous smaller, open source models Microsoft had previously trained
tech5 hours ago
Country is showcasing its attractions at ATM
business6 hours ago