This conference brought together leading orthopedic experts to address the key challenges and advancements in orthopedics and sports medicine
kt network2 hours ago
A baby boy has been born somewhere in the world - what's the big news here? The news is that this baby has become the world's first human being to be born using the revolutionary 'three parent' technique.
Five-month-old A.H. is the first baby to be born using a new technique that incorporates DNA from three parents, New Scientist reported today.
"This is great news and a huge deal," says Dusko Ilic at King's College London, who wasn't involved in the work. "It's revolutionary."The child's Jordanian parents opted for the procedure as the mother, Ibtisam Shaban, carries the genes for Leigh syndrome, a fatal disorder that affects the developing nervous system.
Genes for the disease reside in DNA in the mitochondria, which provide energy for our cells and carry just 37 genes that are passed down to us from our mothers. This is separate from the majority of our DNA, which is housed in each cell's nucleus. Around a quarter of Shaban's mitochondria have the disease-causing mutation. While she is healthy, Leigh syndrome was responsible for the deaths of her first two children - New Scientist.Shaban and her husband, Mahmoud Hassan, sought out the help of John Zhang and his team at the New Hope Fertility Center in New York City.
Ibtisam Shaban and Mahmoud Hassan have been trying to start a family for almost 20 years. Ten years after they married, Shaban became pregnant, but it ended in the first of four miscarriages.yousufk@khaleejtimes.com
In 2005, the couple gave birth to a baby girl. It was then that they discovered the probable cause of their fertility problems: a genetic mutation in Shaban's mitochondria. Their daughter was born with Leigh syndrome, which affects the brain, muscles and nerves of developing infants. Sadly, she died aged six. The couple's second child had the same disorder, and lived for 8 months.
Abrahim was born on April 6, 2016. He is showing no signs of disease - New Scientist
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