Other UAE leaders have also expressed their sorrow on the tragic incident
Halep outplayed Serena's older sister Venus in a 6-2 6-3 third-round victory, a performance she described as her best of the season but the Romanian knows Serena is the bigger obstacle.
"She was (intimidating) when I was younger but now I don't feel intimidated anymore," the 27-year-old told reporters.
"It's going to be huge challenge for me. It's always great to play against Serena because every time I have to learn something from the match."
Halep has lost eight times in nine meetings with Serena, which all came before the American took time off around the birth of her daughter in September 2017.
Should Halep win on Monday, she will join Martina Hingis and Justine Henin as the only players to knock out the Williams sisters in consecutive rounds of a major.
Despite being top of the rankings, Halep does not feel like the superior player against seven-times Melbourne champion Serena.
"For sure she's the best player in the world because she won so many Grand Slams," Halep added.
"I cannot compare my results to her. But in this moment I am confident that I am in this position and I'm positive about it."
Men's top seed Novak Djokovic will continue his quest for a record seventh Australian Open title against 22-year-old Russian Daniil Medvedev, who has reached the last 16 of a Grand Slam for the first time.
Germany's Alexander Zverev meets Canadian Milos Raonic in a battle of big hitters in the afternoon session on Rod Laver Arena.
Other UAE leaders have also expressed their sorrow on the tragic incident
All measures carried out by security entities are in compatibility with the rules stated by the Constitution and laws
Auguste Rodin buries the ghosts of his Guineas flop to win Britain's most famous horse race as Dubai hopefuls disappoint
Their vessel broke down near the coast of Libya and the sailors were taken into captivity by a local militia
The team is looking to complete the treble after bagging the Football Association Cup
The BBC, which is broadcasting the game in Britain, timed the goal at 12.91 seconds
Many of the passengers were still in shock and yet to tell their families that they nearly died in one of the country's worst rail disasters in decades
As per the information received till now from the South Eastern Railway, there are 288 casualties from the Odisha train crash