Emirati Jiu-Jitsu stars win 23 medals, athletes grab 11 medals, and People of Determination excel with 14 medals
Fitzpatrick carded a second round 65 at the Olgiata Golf Club to be 10 under for the tournament, one shot ahead of Denmark's Joachim B. Hansen.
Five players were a further shot back on seven under with former US Open champions Rose and McDowell joined by India's Shubhankar Sharma, Rory Sabbatini of Slovakia and Englishman Andrew Johnston.
The 25-year-old Fitzpatrick has not lifted a trophy since last year's European Masters.
"Just a really, really solid day," said Fitzpatrick. "I figured out something with my irons after the second hole. I just felt much more comfortable with my irons once I was out there. That certainly showed. I only missed one green after that.
"When you're in these kind of positions, it's always exciting. That's why you play the game, and look forward to the weekend."
Defending British Open champion Shane Lowry and Francesco Molinari, the 2018 winner of the Claret Jug, both missed the cut as did Ian Poulter, who chose not to defend his Houston Open title in order to play in Rome.
Emirati Jiu-Jitsu stars win 23 medals, athletes grab 11 medals, and People of Determination excel with 14 medals
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