Obese women prone to hormonal imbalance

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Obese women prone to hormonal imbalance

Polycystic ovary syndrome (PCOS) is a common condition affecting teenage girls and women. It is the syndrome of hormonal imbalance in which there is excessive production of the male hormone testosterone by the female ovary.

By Staff Reporter

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Published: Sat 28 Sep 2013, 9:39 AM

Last updated: Fri 3 Apr 2015, 4:49 AM

Till now there is no agreement about the exact cause of PCOS but one could say that it is more common in females with a positive family history of PCOS or even type 2 diabetes, explains Dr Bashar Neamat Fadheel Sahar, Specialist Internal Medicine Endocrinology, Zulekha Hospital, Dubai. “It is also observed more in obese females. Thus it looks like a combination of nature and nurture are the major contributor of this syndrome.”

The diagnosis of this syndrome is based on the collection of certain criteria with at least two out of the following three:

1. Irregular cycle with delayed or missed periods.

2. Excessive growth of hair on the face and body.

3. Characteristic ovary changes demonstrated by the ultrasound.

Other important symptoms include weight changes, acne, patches of dark skin on the nape of the neck, axillae, cubital fossa.

Careful history taking is of paramount importance. The doctor should take a detailed history of menstrual cycle and should ask about any history of excessive hair growth and its distribution, and not to forget the family history.

Physical examination should start by assessing basic things like measuring the weight and height and calculating the body mass index of the patient. Then one should look for any evidence of excess hair growth and its distribution and its severity. PCOS are closely related to obesity so life style change in the form of diet and exercise is very important. In addition there is a drug treatment which can help to reduce the symptoms of excessive hair growth and to regulate the menstrual cycle.

This can be in the form of hormonal treatment (estrogen and progesterone), and other non-hormonal tablets like metformin and spironolactone which can be very beneficial to ameliorate symptoms if used in combination.

PCOs can affect a woman’s fertility but at the same time there are successful treatment modalities that increase the chances of fertility. -news@khaleejtimes.com



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