GSK will stop selling its blood cancer drug Blenrep in the United States, it said on Tuesday, representing the latest in a series of setbacks for the British drugmaker's oncology business.
The company had said this month that Blenrep failed the main goal of a key study designed to show it was better than an existing treatment on the market, stoking fears that regulatory approval could be rescinded by the US Food and Drug Administration (FDA).
On Tuesday, GSK said it had begun the process to withdraw Blenrep's marketing authorisation in the country, but would continue trial programmes for the drug, adding that some patients would have the option to enrol for continued access to the treatment.
"We will continue the Dreamm clinical trial programme and work with the US FDA on a path forward for this important treatment option for patients with multiple myeloma," GSK Chief Medical Officer Sabine Luik said in a statement.
GSK said access to Blenrep in other countries where it is marketed is unaffected, including across the European Union. The company is still discussing the latest clinical data with EU health authorities, a GSK official said.
The drug was given speedy approval by the FDA in 2020 and approved for patients with relapsed or refractory multiple myeloma who received at least four previous therapies.
Last year, the drug achieved £89 million ($105 million) in global sales, about two thirds of which was from the United States.
Oncology is a key area of focus for GSK as a stand-alone prescription medicine and vaccine business, but the company suffered another blow this month after it had to limit the use of its ovarian cancer drug Zejula in the United States.
Blenrep belongs to a category of treatments called antibody drug conjugates, which are engineered antibodies that bind to tumour cells and then release cell-killing chemicals.
Once ramped up, the new centres are expected to each generate annual revenue of up to Dh200 million
Many residents opt for it in times of financial crunch and other urgent personal needs
Rents are projected to continue the upward trend across the country in 2024
The number of transactions carried out witnessed a significant increase compared to last year
The 57,000 sqm facility incorporates advanced technologies that include automated sort systems
Report notes that the GCC banking sector has experienced steady growth due to infrastructure projects, economic diversification efforts